Prevention

Does Mouthwash Actually Do Anything?

By Douglas Sandquist, DDS

Updated September 19, 2026

If brushing and flossing are the squeegee, and a cleaning is the deep clean, mouthwash is the shower spray that makes the bathroom smell nice. It feels like it’s doing something. It isn’t touching the grout.

That surprises people, because mouthwash sells itself on exactly that feeling: the burn, the mint, the sense of a mouth that’s been scrubbed. For most people, most of the time, a daily rinse doesn’t do much. There are a few situations where the right rinse really earns its place, and one where the wrong one may be doing harm you’d never notice.

What mouthwash can’t do

Plaque is sticky. It clings to the teeth as a film of bacteria, and most mouthwashes are far too mild to break it up. To dissolve plaque with a liquid alone, you’d need something really toxic, the kind of thing you wouldn’t want anywhere near your gums. So a rinse washes over plaque rather than removing it. Taking it off by hand, with a brush and floss, beats any rinse on the shelf.

And once plaque hardens into tartar, no rinse will touch it at all. That takes a professional cleaning.

Even the strongest prescription rinse doesn’t change that picture much. A 2017 Cochrane review of 51 studies found that chlorhexidine, the most powerful antiseptic rinse there is, cut plaque substantially when used alongside brushing, but its effect on gum inflammation in people with mild gingivitis was too small to be considered clinically meaningful.

James P, Worthington HV, Parnell C, et al. Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Cochrane Database Syst Rev. 2017;3:CD008676.

A fresh-feeling mouth isn’t the same as a clean one. If your gums bleed when you brush, a rinse can hide the taste and the smell while the inflammation carries on underneath.

Where a rinse earns its place

After surgery

This is where rinses do their most useful work. After an extraction, gum surgery or implant placement, you can’t brush the area normally, and keeping bacteria down while the tissue heals matters.

Chlorhexidine is the standard prescription rinse for that window. It works, and it’s the right tool for a short stretch. It’s not meant for everyday, long-term use, because it stains teeth brown and can change how food tastes while you’re using it.

StellaLife is a gentler option we like after surgery. In a small 2025 trial of 34 people, it controlled gum inflammation about as well as chlorhexidine, and lab studies show it’s far kinder to the cells that do the healing. The research is still early, small and partly industry-funded, so we treat it as promising rather than proven. What to eat after oral surgery covers the rest of the recovery.

Aslam Z, Wu J, Wang Z, et al. Efficacy of herbal vs. chlorhexidine mouthwash in experimental gingivitis: a cross-over clinical and microbiological study. Dent J (Basel). 2025;13(12):608. Fujioka-Kobayashi M, Schaller B, Pikos MA, et al. Cytotoxicity and gene expression changes of a novel homeopathic antiseptic oral rinse in comparison to chlorhexidine in gingival fibroblasts. Materials (Basel). 2020;13(14):3190.

For people who keep getting cavities

For someone who’s truly decay-prone, a daily fluoride rinse can help. A 2016 Cochrane review of 37 trials in children and teenagers found that regular, supervised fluoride rinsing was associated with about 27% fewer decayed tooth surfaces.

Marinho VC, Chong LY, Worthington HV, Walsh T. Fluoride mouthrinses for preventing dental caries in children and adolescents. Cochrane Database Syst Rev. 2016;7:CD002284.

One important exception: fluoride rinses aren’t for young children. Kids under about six can’t reliably spit instead of swallowing, and swallowing fluoride rinse day after day isn’t something we want. For them, the right amount of fluoride toothpaste does the job.

If fluoride is a no-go for you, there are quite a few other options available today, and some of them are showing real promise. Nano-hydroxyapatite, for example, puts mineral back into enamel without fluoride, and it’s part of the fluoride-free protocol we run here. But whichever you choose, a rinse alone isn’t going to stop cavities. It’s one piece alongside brushing, flossing, what you eat and drink, and how much saliva you have working for you.

For a dry mouth, skip the alcohol

Alcohol-based mouthwash dries and irritates the tissue a dry mouth is already struggling to protect. If you have dry mouth, plain water after meals and a saliva substitute at night do far more than any rinse.

The blood pressure question

This one isn’t on the label, and it’s worth knowing about.

Some of the bacteria in your mouth do a useful job: they convert nitrate from foods like leafy greens and beets into nitrite, which your body turns into nitric oxide. Nitric oxide relaxes blood vessels and helps keep blood pressure in check. Strong antiseptic mouthwashes kill those bacteria along with the rest.

  • In a 2013 study, 19 healthy volunteers used an antiseptic mouthwash for a week. Their mouths’ nitrite production dropped by 90%, and their blood pressure rose by 2 to 3.5 points, starting within a day.
  • A 2020 study followed 540 adults who didn’t have high blood pressure at the start. Those who used over-the-counter mouthwash twice a day or more had 85% higher odds of developing high blood pressure than those who used it less.

Kapil V, Haydar SM, Pearl V, et al. Physiological role for nitrate-reducing oral bacteria in blood pressure control. Free Radic Biol Med. 2013;55:93-100. Joshipura K, Muñoz-Torres F, Fernández-Santiago J, et al. Over-the-counter mouthwash use, nitric oxide and hypertension risk. Blood Press. 2020;29(2):103-112.

The first study was small and short, and the second shows a link rather than proving cause. But the mechanism makes sense, and it points the same way as everything else here: a strong antiseptic rinse used twice a day, every day, for years is doing more than freshening your breath. If you have high blood pressure or a family history of it, that’s one more reason to think twice about the daily habit.

What we recommend

For most people, a mouthwash is optional, and the money is better spent on a good toothbrush and floss. If you like using one, we’re fans of mild, alcohol-free rinses, and we usually suggest starting with CloSYS. StellaLife is a good option too, and if you’d rather avoid fluoride, Swish, a hydroxyapatite rinse, and NOBS Herbal Mouthwash are both alcohol-free and fluoride-free, with xylitol. They freshen without the burn, without drying the mouth, and without wiping out everything that lives there.

For what it’s worth, Dr. Sandquist doesn’t use a rinse himself. He brushes with NOBS toothpaste tablets, which use nano-hydroxyapatite instead of fluoride, and puts his effort into brushing and flossing well.

  • After surgery: chlorhexidine for a short stretch, or StellaLife.
  • Decay-prone adults and older kids: a fluoride rinse, but not for children too young to spit it out.
  • Avoiding fluoride: Swish or NOBS Herbal Mouthwash, with a nano-hydroxyapatite toothpaste doing the real work.
  • Dry mouth: no alcohol-based rinses.
  • Everyone else: a mild, alcohol-free rinse, starting with CloSYS, if you enjoy it, and nothing if you don’t.

Whatever you rinse with, it’s the last step after brushing and flossing, not a substitute for either, and not a substitute for having the tartar removed. The shower spray doesn’t clean the grout.

Worth asking about

If you’re rinsing because your breath or your gums worry you, the rinse is covering a question worth answering. Bad breath that brushing doesn’t fix and gums that bleed both have causes, and a hygiene visit is where they get found.

Call 702-734-0776 or tell us what’s going on.

Common Questions

Is mouthwash necessary?

For most people, no. Plaque is sticky, and most mouthwashes are far too mild to break it up; dissolving it with a liquid alone would take something really toxic. Removing it by hand with a brush and floss beats any rinse. A rinse earns its place in a few situations: after surgery, for people who keep getting cavities, and sometimes for specific gum problems. Otherwise it’s optional.

Can mouthwash replace brushing or flossing?

No. A rinse washes over plaque rather than removing it, and it does nothing at all to tartar, the hardened plaque that only a professional cleaning can remove. Even chlorhexidine, the strongest prescription rinse, reduced gum inflammation by too little to be clinically meaningful in a 2017 Cochrane review, although it cut plaque when used alongside brushing.

What mouthwash do you recommend?

If you like using one, a mild, alcohol-free rinse. We usually suggest starting with CloSYS. StellaLife is a good option too, and for people avoiding fluoride, Swish, a hydroxyapatite rinse, and NOBS Herbal Mouthwash are both alcohol-free and fluoride-free. They freshen without the burn, without drying the mouth, and without wiping out all the bacteria that live there. After surgery we use chlorhexidine for a short stretch or StellaLife, and for decay-prone patients a fluoride rinse can help. Dr. Sandquist doesn’t use a rinse himself; he brushes with NOBS nano-hydroxyapatite toothpaste tablets.

Can mouthwash raise blood pressure?

There’s evidence it can. Some mouth bacteria convert nitrate from foods like leafy greens into nitrite, which the body turns into nitric oxide, a molecule that relaxes blood vessels. Strong antiseptic rinses kill those bacteria. In a 2013 study, a week of antiseptic mouthwash cut the mouth’s nitrite production by 90% and raised blood pressure by 2 to 3.5 points. A 2020 study found that adults using over-the-counter mouthwash twice a day or more had 85% higher odds of developing high blood pressure. The first study was small and short and the second shows a link rather than proof, but they point the same way.

Should I use chlorhexidine mouthwash every day?

Not long term. Chlorhexidine is the right tool for a short stretch after surgery or gum treatment, when you can’t brush an area normally. Used for longer, it stains teeth brown and can change how food tastes, and it wipes out helpful bacteria along with harmful ones.

Is fluoride mouthwash safe for kids?

For older children and teenagers who are decay-prone, a fluoride rinse can help: a 2016 Cochrane review found regular supervised rinsing was associated with about 27% fewer decayed surfaces. It isn’t for young children, though. Kids under about six can’t reliably spit instead of swallowing, and swallowing fluoride rinse every day isn’t something we want. For them, the right amount of fluoride toothpaste does the job.

What if I don’t want to use fluoride?

There are quite a few other options available today, and some are showing real promise. Nano-hydroxyapatite, for example, puts mineral back into enamel without fluoride, and it’s part of the fluoride-free protocol we run here. Dr. Sandquist uses NOBS toothpaste tablets, which are nano-hydroxyapatite based, and Swish and NOBS both make fluoride-free, alcohol-free rinses. But no rinse, fluoride or otherwise, is going to stop cavities on its own. It’s one piece alongside brushing, flossing, what you eat and drink, and how much saliva you have working for you.

Is alcohol-free mouthwash better?

For most people, yes, and for anyone with a dry mouth, definitely. Alcohol-based rinses dry and irritate the tissue, which is the opposite of what a dry mouth needs. A mild, alcohol-free rinse freshens without those downsides.

Wondering what your mouth actually needs?

Tell us what is going on and we will help you find the piece that is missing. No pressure, no obligation.